Seth MacFarlane
Seth MacFarla...
 Capt. Ed Mercer 26 episodes, 2017-2019
Adrianne Palicki
Adrianne Pali...
 Cmdr. Kelly Grayson 26 episodes, 2017-2019
Penny Johnson Jerald
Penny Johnson...
 Dr. Claire Finn 26 episodes, 2017-2019
Scott Grimes
Scott Grimes
 Lt. Gordon Malloy 26 episodes, 2017-2019
Peter Macon
Peter Macon
 Lt. Cmdr. Bortus 26 episodes, 2017-2019
Halston Sage
Halston Sage
 Lt. Alara Kitan 26 episodes, 2017-2019
J. Lee
J. Lee
 Lt. Cmdr. John LaMarr / ... 26 episodes, 2017-2019
Mark Jackson
Mark Jackson
 Isaac 26 episodes, 2017-2019
Jessica Szohr
Jessica Szohr
 Talla 14 episodes, 2018-2019